Reducing Suicide Risk Through Targeted Pharmacological Strategies

Speaker: Thanompong Sathienluckana
Siam University, Thailand
Session Type: Oral Presentation 
Talk Title: Pharmacological pathways for suicide reduction inpsychiatric patients

🧠 Session Overview
∙ A Critical Global Issue: Suicide remains a leading cause of death globally, with over 700,000 deaths each year and a strong association with psychiatric disorders.
∙ Understanding the Biology: This talk explores key neurobiological mechanisms involved in suicidality, including serotonin dysregulation, neuroinflammation, reduced BDNF, and HPA-axis hyperactivity.
∙ Current Treatment Gaps: Despite advances in psychiatry, no medication is specifically approved for acute suicidal crises—highlighting the need for optimized pharmacotherapy.
∙ Risk-Focused Management: Emphasis on addressing contributory factors such as sleep problems, substance use, medication non-adherence, comorbid illnesses, and psychosocial stressors.
∙ Evidence-Based Medications:
– Clozapine: Proven to lower suicide risk in schizophrenia and schizoaffective disorder, with effects beyond antipsychotic action.
– Lithium: Demonstrates robust anti-suicidal benefits in mood disorders, independent of mood stabilization.
– Ketamine & Intranasal Esketamine: Rapid-onset reduction of depressive symptoms and suicidal ideation in treatment-resistant depression.
– SSRIs: Effective in reducing suicide risk in adults and older populations, with age-specific considerations in younger patients.
∙ Clinical Insight: Highlights the importance of correct dosing, continuity of treatment, and close monitoring to prevent relapse and suicidality.

👨‍⚕️ Meet the Speaker
Thanompong Sathienluckana, PharmD, BCP, serves as Associate Dean for Academic Services at the Faculty of Pharmacy, Siam University, and Academic Chair of the Pharmacotherapy Council of Thailand.
∙ Clinical pharmacist at Somdet Chaopraya Institute of Psychiatry, Bangkok
∙ Specialist in neurologic and psychiatric pharmaceutical care
∙ PharmD graduate from Srinakharinwirot University
∙ Board Certified in Pharmacotherapy

🔗 Attend the Conference
International Conference on Addiction Medicine, Mental Health and Psychiatry
📅 March 23–25, 2026
📍 Singapore & Online
📝 Register Now: https://addiction.miconferences.com/register

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