The intricate relationship between dopamine genetics and immune function takes center stage in a thought-provoking presentation by Dr. San-Yuan Huang from the National Defense Medical Center, Taiwan, at the International Conference on Addiction Medicine, Mental Health and Psychiatry (ICAMP 2026).
🔬
Understanding the Study
Dr.
Huang’s research focuses on how dopamine receptor D3 (DRD3) gene variations
influence inflammatory
cytokine responses during amphetamine abstinence. The study,
involving 72
female patients with amphetamine dependence and 51 healthy
controls, explores how genetics may shape recovery in
addiction-related immune imbalances.
📊 Key Findings
·
Amphetamine-dependent patients exhibited increased levels of Th1 (IL-2)
and Th2
cytokines (IL-4, IL-5, IL-6, IL-10) at baseline.
·
After 4 weeks of abstinence, levels of IL-8 and
IL-10 decreased significantly.
·
Individuals carrying the DRD3 rs6280 TT genotype showed more favorable
immune recovery compared to C allele carriers, who maintained higher IL-2
and IL-6
levels.
·
Results indicate that chronic amphetamine use disrupts immune balance,
and recovery patterns may depend on genetic profiles.
👨⚕️ About Dr. San-Yuan Huang
Dr.
Huang is a distinguished psychiatrist and neuroscientist with expertise in gene-environment
interactions in addiction and mental health. Holding both M.D. and
Ph.D. degrees from the National Defense Medical Center, he has
contributed extensively to research on psycho-immunology, neuroimaging (SPECT & PET),
and genetic
influences on addiction recovery.
🌐 Event
Details
Event Name: International
Conference on Addiction Medicine, Mental Health and Psychiatry
📅 Dates:
March 23–25, 2026
📍 Venue:
Singapore & Online
🔗 https://addiction.miconferences.com/
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